Detalhe da pesquisa
1.
A Deep Learning Approach to Antibiotic Discovery.
Cell
; 180(4): 688-702.e13, 2020 02 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-32084340
2.
A Comprehensive, CRISPR-based Functional Analysis of Essential Genes in Bacteria.
Cell
; 165(6): 1493-1506, 2016 Jun 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27238023
3.
A Deep Learning Approach to Antibiotic Discovery.
Cell
; 181(2): 475-483, 2020 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-32302574
4.
Identification of drugs including a dopamine receptor antagonist that selectively target cancer stem cells.
Cell
; 149(6): 1284-97, 2012 Jun 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-22632761
5.
Central metabolism is a key player in E. coli biofilm stimulation by sub-MIC antibiotics.
PLoS Genet
; 19(11): e1011013, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37917668
6.
CARD 2023: expanded curation, support for machine learning, and resistome prediction at the Comprehensive Antibiotic Resistance Database.
Nucleic Acids Res
; 51(D1): D690-D699, 2023 01 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36263822
7.
A genetic platform to investigate the functions of bacterial drug efflux pumps.
Nat Chem Biol
; 18(12): 1399-1409, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36065018
8.
An Omniphobic Spray Coating Created from Hierarchical Structures Prevents the Contamination of High-Touch Surfaces with Pathogens.
Small
; 19(12): e2205761, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36587985
9.
Transparent and Highly Flexible Hierarchically Structured Polydimethylsiloxane Surfaces Suppress Bacterial Attachment and Thrombosis Under Static and Dynamic Conditions.
Small
; 18(15): e2108112, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35224860
10.
A multiplexable assay for screening antibiotic lethality against drug-tolerant bacteria.
Nat Methods
; 16(4): 303-306, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30858599
11.
Systems-Level Chemical Biology to Accelerate Antibiotic Drug Discovery.
Acc Chem Res
; 54(8): 1909-1920, 2021 04 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-33787225
12.
Discovery of an antivirulence compound that reverses ß-lactam resistance in MRSA.
Nat Chem Biol
; 16(2): 143-149, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31768032
13.
Antibacterial drug discovery in the resistance era.
Nature
; 529(7586): 336-43, 2016 Jan 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-26791724
14.
Crystallographic analysis of TarI and TarJ, a cytidylyltransferase and reductase pair for CDP-ribitol synthesis in Staphylococcus aureus wall teichoic acid biogenesis.
J Struct Biol
; 213(2): 107733, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33819634
15.
Crystallographic analysis of Staphylococcus aureus LcpA, the primary wall teichoic acid ligase.
J Biol Chem
; 295(9): 2629-2639, 2020 02 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-31969390
16.
Physicochemical and Structural Parameters Contributing to the Antibacterial Activity and Efflux Susceptibility of Small-Molecule Inhibitors of Escherichia coli.
Antimicrob Agents Chemother
; 65(4)2021 03 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-33468483
17.
Structure and mechanism of TagA, a novel membrane-associated glycosyltransferase that produces wall teichoic acids in pathogenic bacteria.
PLoS Pathog
; 15(4): e1007723, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31002736
18.
A whole-cell, high-throughput hydrogenase assay to identify factors that modulate [NiFe]-hydrogenase activity.
J Biol Chem
; 294(42): 15373-15385, 2019 10 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-31455635
19.
Meropenem potentiation of aminoglycoside activity against Pseudomonas aeruginosa: involvement of the MexXY-OprM multidrug efflux system.
J Antimicrob Chemother
; 73(5): 1247-1255, 2018 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29420743
20.
Structure and Mechanism of Staphylococcus aureus TarS, the Wall Teichoic Acid ß-glycosyltransferase Involved in Methicillin Resistance.
PLoS Pathog
; 12(12): e1006067, 2016 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-27973583